HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-(dimethylamino)ethyl)-3-methoxy-4-nitrobenzamide → 4-amino-N-(2-(dimethylamino)ethyl)-3-methoxybenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-(dimethylamino)ethyl)-3-methoxy-4-nitrobenzamide | HCID 68683674 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-amino-N-(2-(dimethylamino)ethyl)-3-methoxybenzamide | HCID 58015042 | — |
Reaction Steps
To a suspension of the product of Example 31A (5.4 g, 20.2 mmol) in methanol (200 mL) was added 10% palladium on carbon (540 mg) and the mixture was stirred under hydrogen for 4 hours. The catalyst was filtered off and the filtrate was concentrated to give the title compound. MS: 238 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09212192B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-13c5866269c840dbb9b3571e5ed8a9fc |
| Source note | uspto-grants-2015_12 |