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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1503849Generated: October 26, 2026

N-(2-(dimethylamino)ethyl)-3-methoxy-4-nitrobenzamide → 4-amino-N-(2-(dimethylamino)ethyl)-3-methoxybenzamide

https://huagongshe.com/reaction/1503849

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(2-(dimethylamino)ethyl)-3-methoxy-4-nitrobenzamideHCID 68683674—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product4-amino-N-(2-(dimethylamino)ethyl)-3-methoxybenzamideHCID 58015042—

Reaction Steps

To a suspension of the product of Example 31A (5.4 g, 20.2 mmol) in methanol (200 mL) was added 10% palladium on carbon (540 mg) and the mixture was stirred under hydrogen for 4 hours. The catalyst was filtered off and the filtrate was concentrated to give the title compound. MS: 238 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09212192B2
Source datasetuspto-grants-2015_12
ORD IDord-13c5866269c840dbb9b3571e5ed8a9fc
Source noteuspto-grants-2015_12