(3-Methoxy-4-nitrophenyl)(4-methylpiperazin-1-yl)methanone → (4-Amino-3-methoxyphenyl)(4-methylpiperazin-1-yl)methanone

Participants

Reaction Steps

To a solution of Example 37A (9 g, 32 mmol) in methanol (100 mL) was added 10% palladium on carbon (1 g) and the mixture was stirred at ambient temperature under hydrogen for 8 hours. The mixture was filtered and the filtrate was concentrated to provide the title compound. MS: 250.2 (M+H+).

Provenance & Evidence