Ethyl orthopropionate → HCID 86725415, compound

Participants

Reaction Steps

To a solution of the product of Example 55B (250 mg, 0.49 mmol) was added 1,1,1-triethoxypropane (3 mL) and the mixture was stirred at ambient temperature for 1 hour and heated at 55° C. for 5 hours. After cooling, 90/10 petroleum ether/ethyl acetate was added and the precipitate was collected. The solid was washed with petroleum ether and dried under vacuum to give the title compound. MS: 546 (M+H+).

Provenance & Evidence