反应详情

6-(3-Amino-propoxy)-1-methyl-1H-quinolin-2-one(194 mg) was added to an ethanol solution (5 ml) of N-methyl-N-o-tolyl-acrylamide(146 mg). The mixture was stirred at room temperature overnight. The reaction mixture was condensed under reduced pressure. The residue was purified by silica gel column chromatography (dichloromethane: methanol=20:1→10:1). The purified product was condensed under reduced pressure to give the title compound(172.6 mg) as a colorless oil.

1. customcondensed under reduced pressure
2. customThe residue was purified by silica gel column chromatography (dichloromethane: methanol=20:1→10:1)
3. customcondensed under reduced pressure