Cyclopentanemethanol → HCID 80877471, compound

HRID 1504556Notes

Reaction equation

HRID 1504556 reaction equation
[CH:1]1([CH2:4][O:5][C:6]2[N:11]=[CH:10][N:9]=[C:8]([NH2:12])[CH:7]=2)[CH2:3][CH2:2]1.[CH:13]1(CO)CCC[CH2:14]1>>[CH:1]1([CH2:4][O:5][C:6]2[N:11]=[CH:10][N:9]=[C:8]([NH2:12])[CH:7]=2)[CH2:3][CH2:2][CH2:14][CH2:13]1

Participants

3

Reactant 2

HCID 77195CyclopentanemethanolHCID 80864926HCID 80864926, compound

Product 1

HCID 80877471HCID 80877471, compoundYield 89%

Procedure

This was prepared in a manner analogous to 6-(cyclopropylmethoxy)pyrimidin-4-amine, where cyclopentylmethanol was used as the alcohol. 6-(cyclopentylmethoxy)pyrimidin-4-amine (0.266 g, 1.376 mmol, 89% yield) was obtained as a white solid. m/z (ESI) 194.2 (M+H)+.

Sources & evidence

ORD record
ord-089e36b0e42449bdb143b3c927ef1a9d
Source dataset
uspto-grants-2015_12
Patent number
US09212182B2

Reaction notes

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