Sodium Chloride → 38916-34-6

HRID 1504743Notes

Reaction equation

HRID 1504743 reaction equation
[Cl-].[Na+].[CH3:3][CH:4]([OH:117])[CH:5]1[NH:53][C:51](=[O:52])[CH:50]([CH2:54][CH2:55][CH2:56][CH2:57][NH2:58])[NH:49][C:47](=[O:48])[CH:46]([CH2:59][C:60]2[C:68]3[C:63](=[CH:64][CH:65]=[CH:66][CH:67]=3)[NH:62][CH:61]=2)[NH:45][C:43](=[O:44])[CH:42]([CH2:69][C:70]2[CH:75]=[CH:74][CH:73]=[CH:72][CH:71]=2)[NH:41][C:39](=[O:40])[CH:38]([CH2:76][C:77]2[CH:82]=[CH:81][CH:80]=[CH:79][CH:78]=2)[NH:37][C:35](=[O:36])[CH:34]([CH2:83][C:84]([NH2:86])=[O:85])[NH:33][C:31](=[O:32])[CH:30]([CH2:87][CH2:88][CH2:89][CH2:90][NH2:91])[NH:29][C:27](=[O:28])[CH:26]([NH:92][C:93]([CH2:95][NH:96][C:97]([CH:99]([NH2:101])[CH3:100])=[O:98])=[O:94])[CH2:25][S:24][S:23][CH2:22][CH:21]([C:102]([OH:104])=[O:103])[NH:20][C:18](=[O:19])[CH:17]([CH2:105][OH:106])[NH:16][C:14](=[O:15])[CH:13]([CH:107]([OH:109])[CH3:108])[NH:12][C:10](=[O:11])[CH:9]([CH2:110][C:111]2[CH:116]=[CH:115][CH:114]=[CH:113][CH:112]=2)[NH:8][C:6]1=[O:7]>>[CH3:3][C@@H:4]([OH:117])[C@@H:5]1[NH:53][C:51](=[O:52])[C@H:50]([CH2:54][CH2:55][CH2:56][CH2:57][NH2:58])[NH:49][C:47](=[O:48])[C@H:46]([CH2:59][C:60]2[C:68]3[CH:67]=[CH:66][CH:65]=[CH:64][C:63]=3[NH:62][CH:61]=2)[NH:45][C:43](=[O:44])[C@H:42]([CH2:69][C:70]2[CH:75]=[CH:74][CH:73]=[CH:72][CH:71]=2)[NH:41][C:39](=[O:40])[C@H:38]([CH2:76][C:77]2[CH:78]=[CH:79][CH:80]=[CH:81][CH:82]=2)[NH:37][C:35](=[O:36])[C@H:34]([CH2:83][C:84]([NH2:86])=[O:85])[NH:33][C:31](=[O:32])[C@H:30]([CH2:87][CH2:88][CH2:89][CH2:90][NH2:91])[NH:29][C:27](=[O:28])[C@@H:26]([NH:92][C:93]([CH2:95][NH:96][C:97]([C@@H:99]([NH2:101])[CH3:100])=[O:98])=[O:94])[CH2:25][S:24][S:23][CH2:22][C@@H:21]([C:102]([OH:104])=[O:103])[NH:20][C:18](=[O:19])[C@H:17]([CH2:105][OH:106])[NH:16][C:14](=[O:15])[C@H:13]([C@H:107]([OH:109])[CH3:108])[NH:12][C:10](=[O:11])[C@H:9]([CH2:110][C:111]2[CH:112]=[CH:113][CH:114]=[CH:115][CH:116]=2)[NH:8][C:6]1=[O:7]

Participants

3

Reactant 2

HCID 5234Sodium ChlorideHCID 1612968151110-01-1

Product 1

HCID 1612970638916-34-6

Procedure

A pharmaceutical composition of somatostatin was prepared in the form of eye drops by adding 1 mL of 0.9% sodium chloride and 1.4% poly(vinyl alcohol) aqueous solution to 0.27 mg of somatostatin-14. Finally, the solution was filtered through a 0.22 μm sterilizing filter.

Workup

  1. filtrationFinally, the solution was filtered through a 0.22 μm
  2. filtrationsterilizing filter

Sources & evidence

ORD record
ord-eb7a7f03d7b64e06964a7478634d012e
Source dataset
uspto-grants-2015_12
Patent number
US09216208B2

Reaction notes

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