HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 46523747, compound → HCID 58317894, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 46523747 | HCID 46523747 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 58317894 | HCID 58317894 | — |
Reaction Steps
To a solution of 2-methyl-5-nitro-N-phenylnicotinamide (460 mg, 1.79 mmol) in 20 mL of ethanol is added Pd/C (40 mg). The reaction mixture is stirred under H2 atmosphere for 15 hours. The Pd/C is removed by filtering through a celite pad. The filtrate is dried to afford 5-amino-2-methyl-N-phenylnicotinamide as an off-white solid. MS m/z 228.1 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09216964B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-be5b187cd7924435bc38cfcad9ad8951 |
| Source note | uspto-grants-2015_12 |