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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1505059Generated: October 31, 2026

HCID 46523747, compound → HCID 58317894, compound

https://huagongshe.com/reaction/1505059

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 46523747HCID 46523747—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 58317894HCID 58317894—

Reaction Steps

To a solution of 2-methyl-5-nitro-N-phenylnicotinamide (460 mg, 1.79 mmol) in 20 mL of ethanol is added Pd/C (40 mg). The reaction mixture is stirred under H2 atmosphere for 15 hours. The Pd/C is removed by filtering through a celite pad. The filtrate is dried to afford 5-amino-2-methyl-N-phenylnicotinamide as an off-white solid. MS m/z 228.1 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09216964B2
Source datasetuspto-grants-2015_12
ORD IDord-be5b187cd7924435bc38cfcad9ad8951
Source noteuspto-grants-2015_12