HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyl-4-(methyloxy)-2-[(4-nitrophenyl)oxy]benzene → 4-{[2-Methyl-5-(methyloxy)phenyl]oxy}aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyl-4-(methyloxy)-2-[(4-nitrophenyl)oxy]benzene | HCID 67235921 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-{[2-Methyl-5-(methyloxy)phenyl]oxy}aniline | HCID 67235971 | 90.5% |
Reaction Steps
A suspension of 1-methyl-4-(methyloxy)-2-[(4-nitrophenyl)oxy]benzene (Intermediate 13, 2.5 g) and Pd/C (10%, 1 g) in MeOH (100 mL) was stirred under H2 atmosphere for overnight at room temperature and filtered through a pad of celite. The filtrate was evaporated to afford the title compound as a solid (2.0 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09216967B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-d8909cecd71d4a189a3ae8b688460389 |
| Source note | uspto-grants-2015_12 |