HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 16641866, compound → HCID 68322476, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 16641866 | HCID 16641866 | — |
| Reactant | HCID 16788418 | HCID 16788418 | — |
| Reactant | HCID 86673582 | HCID 86673582 | — |
| Product | HCID 68322476 | HCID 68322476 | — |
Reaction Steps
The title compound was made in a similar fashion to the preparation of Intermediate 25 replacing 6-{[3-(1-methylethyl)phenyl]oxy}-3-pyridinamine with 6-[(2,5-dimethylphenyl)oxy]-3-pyridinamine (Intermediate 34) and using the following conditions for the silica gel chromatography: Companion instrument, 12 g cartridge, a gradient cHex/EtOAc as eluent from 100/0 to 70/30. This afforded the title compound as a light brown oil (63 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09216967B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-8653871dfb9f452b8607b5539b08bb22 |
| Source note | uspto-grants-2015_12 |