反应详情

After dissolving the tert-butyl-2,6-difluoro-3-nitrophenylcarbamate (1 g, 3.6 mmol) prepared at Step 2 in methanol solvent, palladium carbon (100 mg) was added and stirred under hydrogen pressure for 15 hours. After completing the reaction, filtering through celite, vacuum concentrating, and refining by means of column chromatography, 0.76 mg of the target compound, tert-butyl-3-amino-2,6-difluorophenylcarbamate (percentage yield: 86%), was obtained.

1. customthe reaction
2. filtrationfiltering through celite, vacuum
3. concentrationconcentrating