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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1505723Generated: November 1, 2026

Thionyl Chloride → HCID 86691992, compound

https://huagongshe.com/reaction/1505723

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
ReactantHCID 86691993HCID 86691993—
SolventPyridineHCID 1049—
ProductHCID 86691992HCID 8669199288.7%

Reaction Steps

The 7-hydroxy-N-isopropyl-6-phenethyl-7-(trifluoromethyl)-3,4,6,7-tetrahydro-[1,4]diazepino[6,7,1-hi]indole-2(1H)-carboxamide (9 mg, 0.021 mmol) was further processed with SOCl2 and pyridine as described in Example 1, above to yield N-isopropyl-6-phenethyl-7-(trifluoromethyl)-3,4-dihydro-[1,4]diazepino[6,7,1-hi]indole-2(1H)-carboxamide (8 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09216998B2
Source datasetuspto-grants-2015_12
ORD IDord-d4530381d6124806a3831b8c733e8d23
Source noteuspto-grants-2015_12