Dimethylamine methanol → HCID 90313573, compound

HRID 1505778Notes

Reaction equation

HRID 1505778 reaction equation
Cl[CH2:2][C:3]1[NH:7][C:6]2[CH:8]=[C:9]([N+:16]([O-:18])=[O:17])[CH:10]=[C:11]([C:12]([O:14][CH3:15])=[O:13])[C:5]=2[N:4]=1.[CH3:19][NH:20][CH3:21].CO>C(#N)C>[CH3:19][N:20]([CH2:2][C:3]1[NH:7][C:6]2[CH:8]=[C:9]([N+:16]([O-:18])=[O:17])[CH:10]=[C:11]([C:12]([O:14][CH3:15])=[O:13])[C:5]=2[N:4]=1)[CH3:21]

Participants

4

Reactant 2

HCID 22497844Dimethylamine methanolHCID 90229430HCID 90229430, compound

Product 1

HCID 90313573HCID 90313573, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Conditions

Temperature
80 °C

Procedure

To a solution of methyl 2-(chloromethyl)-6-nitro-1H-benzimidazole-4-carboxylate (72 mg) in acetonitrile (3 mL), was added 2M dimethylamine/MeOH solution (1.3 mL), and the mixture was stirred at 80° C. overnight.

Sources & evidence

ORD record
ord-293d3d8b4d98484bb2cef5355565688e
Source dataset
uspto-grants-2015_12
Patent number
US09216968B2

Reaction notes

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