Iodoethane → HCID 67027655, compound

Participants

Reaction Steps

Ethyl iodide (0.6 mL, 7.32 mmol) was added to a solution of 6,8-dimethoxy-3,4-dihydroisoquinoline (700 mg, 3.66 mmol) in acetonitrile (15 mL) and the mixture was left to stir in the dark for 20 h. The resultant precipitate was collected by filtration, washed with acetonitrile and left to air dry to afford the title compound as a yellow solid (750 mg, 95%). 1H NMR (CD3OD, 300 MHz): 8.96 (s, 1H), 6.63 (d, J=2.2 Hz, 1H), 6.61 (d, J=2.2 Hz, 1H), 4.02-3.88 (m, 7H), 3.18 (t, J=7.9 Hz, 2H), 2.03 (s, 5H), 1.47 (t, J=7.3 Hz, 3H).

Provenance & Evidence