Acetic Anhydride → (4-Methylpenta-2,4-dien-2-yl)phosphonic acid

HRID 1506079Notes

Reaction equation

HRID 1506079 reaction equation
O=[C:2]([CH:4]=[C:5]([CH3:7])[CH3:6])[CH3:3].[P:8]([OH:11])([OH:10])[OH:9].C(OC(=O)C)(=O)C>C(O)(=O)C>[CH3:6][C:5](=[CH2:7])[CH:4]=[C:2]([P:8]([OH:11])(=[O:9])[OH:10])[CH3:3]

Participants

5

Reactant 3

HCID 7918Acetic AnhydrideHCID 8858Mesityl oxideHCID 107909Phosphorous acid

Product 1

HCID 54322802(4-Methylpenta-2,4-dien-2-yl)phosphonic acid

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

For example, mesityl oxide, was reacted with phosphorous acid in the presence of acetic anhydride and acetic acid under mild conditions to yield 4-methylpenta-2,4-diene-2-phosphonic acid in more than 90% mole purity.

Sources & evidence

ORD record
ord-445114e17ca34d2ab059313f2bfb6327
Source dataset
uspto-grants-2015_12
Patent number
US09217085B2

Reaction notes

Loading…