HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1506530Generated: October 30, 2026
3-Phenyl-4-(trifluoromethyl)-5-(7-vinyl-4,5-dihydronaphtho[2,1-d]thiazol-2-yl)isoxazole → Ethyl 2-(diphenylmethyleneamino)-4-(2-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-4,5-dihydronaphtho[2,1-d]thiazol-7-yl)butanoate
https://huagongshe.com/reaction/1506530
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Phenyl-4-(trifluoromethyl)-5-(7-vinyl-4,5-dihydronaphtho[2,1-d]thiazol-2-yl)isoxazole | HCID 67170584 | — |
| Reactant | Ethyl 2-(diphenylmethyleneamino)-4-(3-(5-phenyl-4-(trifluoromethyl)isoxazol-3-yl)-4,5-dihydronaphtho[1,2-c]isoxazol-7-yl)butanoate | HCID 86669931 | — |
| Product | Ethyl 2-(diphenylmethyleneamino)-4-(2-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-4,5-dihydronaphtho[2,1-d]thiazol-7-yl)butanoate | HCID 86669934 | — |
Reaction Steps
The titled compound was prepared using the experimental protocol described for Preparation 91A employing 3-phenyl-4-(trifluoromethyl)-5-(7-vinyl-4,5-dihydronaphtho[2,1-d]thiazol-2-yl)isoxazole (Preparation 82E) as a starting material. The reaction was heated at 70° C. for 7 hr. The compound had an LC/MS M+1=692.4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09216972B2 |
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| Source dataset | uspto-grants-2015_12 |
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| ORD ID | ord-7c834895f8de4128839d1605afaa92cd |
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| Source note | uspto-grants-2015_12 |
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