HCID 67168162, compound → 7-Iodo-3-(5-phenyl-4-(trifluoromethyl)isoxazol-3-yl)-4,5-dihydronaphtho[1,2-c]isoxazole

Participants

Role	Name	HCID	Charge
Reactant	HCID 67168162	HCID 67168162	—
Reactant	3-(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)-7-vinyl-4,5-dihydronaphtho[1,2-c]isoxazole	HCID 67170420	—
Reactant	(NE)-N-(6-iodo-3,4-dihydro-2H-naphthalen-1-ylidene)hydroxylamine	HCID 140592659	—
Product	7-Iodo-3-(5-phenyl-4-(trifluoromethyl)isoxazol-3-yl)-4,5-dihydronaphtho[1,2-c]isoxazole	HCID 67171469	—

Reaction Steps

The titled compound was prepared using the experimental protocol described for Preparation 89A employing (E)-6-iodo-3,4-dihydronaphthalen-1(2H)-one oxime (121A) and methyl 5-phenyl-4-(trifluoromethyl)isoxazole-3-carboxylate (Intermediate I-5) as starting materials. The compound had an HPLC retention time=4.42 min. (condition C); LC/MS M+1=509.0.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09216972B2
Source dataset	uspto-grants-2015_12
ORD ID	ord-8b415f84974f471fa71953461d3b0ef1
Source note	uspto-grants-2015_12