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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 15066Generated: October 25, 2026

4-Benzyloxy-2(1H)-pyridone → 4-(4-fluorobenzyloxy)-1-(4-hydroxyphenyl)-1H-pyrimidin-2-one

https://huagongshe.com/reaction/15066

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Benzyloxy-2(1H)-pyridoneHCID 3607724—
Reactant4-benzyloxy-1-{4-[2-(dimethylamino)ethoxy]phenyl}-1H-pyridin-2-oneHCID 11559625—
ReactantHCID 178518416HCID 178518416—
Product4-(4-fluorobenzyloxy)-1-(4-hydroxyphenyl)-1H-pyrimidin-2-oneHCID 68430376—

Reaction Steps

Steps (3) and (4) of Example 1 were repeated except that 4-benzyloxy-1H-pyridin-2-one which was used in Step (3) of Example 1 was replaced with 4-(4-fluorobenzyloxy)-1H-pyrimidin-2-one, to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07732456B2
Source datasetuspto-grants-2010_06
ORD IDord-e56c0d021ff44232a5d711bf5c79d02b
Source noteuspto-grants-2010_06