tert-Butylsulfinamide, (S)-(-)- → (NZ)-N-[[2-(4-chlorophenyl)-1,3-oxazol-5-yl]methylidene]-2-methylpropane-2-sulfinamide

HRID 1506642Notes

Reaction equation

HRID 1506642 reaction equation
COC1C=CC(N2C=CN=C2C=[N:15][S@@:16]([C:18]([CH3:21])([CH3:20])[CH3:19])=[O:17])=CC=1.[Cl:22][C:23]1[CH:28]=[CH:27][C:26]([C:29]2[O:30][C:31]([CH:34]=O)=[CH:32][N:33]=2)=[CH:25][CH:24]=1.CC([S@@](N)=O)(C)C>>[Cl:22][C:23]1[CH:28]=[CH:27][C:26]([C:29]2[O:30][C:31](/[CH:34]=[N:15]\[S:16]([C:18]([CH3:21])([CH3:20])[CH3:19])=[O:17])=[CH:32][N:33]=2)=[CH:25][CH:24]=1

Participants

4

Reactant 3

HCID 11355477tert-Butylsulfinamide, (S)-(-)-HCID 821265782-(4-Chlorophenyl)oxazole-5-carbaldehydeHCID 90281518(R)-N-((1-(4-methoxyphenyl)-1H-imidazol-2-yl)methylene)-2-methylpropane-2-sulfinamide

Product 1

HCID 90280405(NZ)-N-[[2-(4-chlorophenyl)-1,3-oxazol-5-yl]methylidene]-2-methylpropane-2-sulfinamide

Procedure

The title compound was prepared according to the method presented for the synthesis of compound 5B of Example 5 utilizing 19B and (S)-2-methylpropane-2-sulfinamide. MS (m/z) 311.1 [M+H]+.

Sources & evidence

ORD record
ord-38dae8ca9f1c4b9fb5a971be96a62e52
Source dataset
uspto-grants-2015_12
Patent number
US09220710B2

Reaction notes

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