Acridine, 3,9-dichloro- → HCID 71471618, compound

HRID 1506759Notes

Reaction equation

HRID 1506759 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[C:14]([CH:15]=1)=[N:13][C:12]1[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=1)[C:6]=2Cl.[CH2:17]([N:19]1[CH2:24][CH2:23][CH:22]([NH2:25])[CH2:21][CH2:20]1)[CH3:18]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[C:14]([CH:15]=1)=[N:13][C:12]1[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=1)[C:6]=2[NH:25][CH:22]1[CH2:23][CH2:24][N:19]([CH2:17][CH3:18])[CH2:20][CH2:21]1

Participants

3

Reactant 2

HCID 147613Acridine, 3,9-dichloro-HCID 37349901-Ethylpiperidin-4-amine

Product 1

HCID 71471618HCID 71471618, compound

Procedure

Following the general procedure of Example 1 and making non-critical variations, but using 3,9-dichloroacridine (J. Med. Chem. 1985, 28. 940-944) and 1-ethylpiperidin-4-amine, the title compound was obtained; MS (Found M+1=340).

Sources & evidence

ORD record
ord-784f2f2b44ca4eae9e40e2d7e4828978
Source dataset
uspto-grants-2015_12
Patent number
US09221760B2

Reaction notes

Loading…