N-(benzyloxycarbonyl)-4-(mesyloxy)butylamine → HCID 70983743, compound

HRID 1506763Notes

Reaction equation

HRID 1506763 reaction equation
CS(O[CH2:6][CH2:7][CH2:8][CH2:9][NH:10][C:11]([O:13][CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[O:12])(=O)=O.[CH2:21]([NH:23][CH:24]1[CH2:26][CH2:25]1)[CH3:22]>>[CH:24]1([N:23]([CH2:21][CH3:22])[CH2:6][CH2:7][CH2:8][CH2:9][NH:10][C:11](=[O:12])[O:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH2:26][CH2:25]1

Participants

3

Reactant 2

HCID 11141145N-(benzyloxycarbonyl)-4-(mesyloxy)butylamineHCID 13112619N-Ethylcyclopropanamine

Product 1

HCID 70983743HCID 70983743, compound

Procedure

Following the general procedure of Example 4, Step 2, and making non-critical variations but using 4-(benzyloxycarbonylamino)butyl methanesulfonate and commercially available N-ethylcyclopropanamine, benzyl 4-(cyclopropyl(ethyl)amino)butylcarbamate was obtained.

Sources & evidence

ORD record
ord-151b983b5bc24b87ac66f91387720926
Source dataset
uspto-grants-2015_12
Patent number
US09221760B2

Reaction notes

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