1-Ethylpiperidin-4-amine → HCID 71471689, compound

HRID 1506769Notes

Reaction equation

HRID 1506769 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:13](=[CH:14][CH:15]=1)[C:12](Cl)=[C:11]1[C:6]([CH:7]=[CH:8][C:9]([F:17])=[CH:10]1)=[N:5]2.[CH2:18]([N:20]1[CH2:25][CH2:24][CH:23]([NH2:26])[CH2:22][CH2:21]1)[CH3:19]>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:13](=[CH:14][CH:15]=1)[C:12]([NH:26][CH:23]1[CH2:24][CH2:25][N:20]([CH2:18][CH3:19])[CH2:21][CH2:22]1)=[C:11]1[C:6]([CH:7]=[CH:8][C:9]([F:17])=[CH:10]1)=[N:5]2

Participants

3

Reactant 2

HCID 37349901-Ethylpiperidin-4-amineHCID 85806820HCID 85806820, compound

Product 1

HCID 71471689HCID 71471689, compound

Procedure

Following the general procedure of Example 1 and making non-critical variations but using 6,9-dichloro-2-fluoroacridine (J. Med. Chem. 1985, 28. 940-944) and 1-ethylpiperidin-4-amine, the title compound was obtained; MS (Found M+1=358).

Sources & evidence

ORD record
ord-e87ae057219e46bf934f9f68103f9cc8
Source dataset
uspto-grants-2015_12
Patent number
US09221760B2

Reaction notes

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