4-Methylpiperazine-1-ethylamine → HCID 71471690, compound

HRID 1506771Notes

Reaction equation

HRID 1506771 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[C:14]([CH:15]=1)=[N:13][C:12]1[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=1)[C:6]=2Cl.[CH3:17][N:18]1[CH2:23][CH2:22][N:21]([CH2:24][CH2:25][NH2:26])[CH2:20][CH2:19]1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[C:14]([CH:15]=1)=[N:13][C:12]1[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=1)[C:6]=2[NH:26][CH2:25][CH2:24][N:21]1[CH2:22][CH2:23][N:18]([CH3:17])[CH2:19][CH2:20]1

Participants

3

Reactant 2

HCID 702844-Methylpiperazine-1-ethylamineHCID 147613Acridine, 3,9-dichloro-

Product 1

HCID 71471690HCID 71471690, compound

Procedure

Following the general procedure of Example 1 and making non-critical variations but using 3,9-dichloroacridine (J. Med. Chem. 1985, 28. 940-944) and 2-(4-methylpiperazin-1-yl)ethanamine, the title compound was obtained; MS (Found M+1=355).

Sources & evidence

ORD record
ord-1299c81fcc3b4856afd3f872e955caf5
Source dataset
uspto-grants-2015_12
Patent number
US09221760B2

Reaction notes

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