6,9-Dichloro-1,2,3,4-tetrahydroacridine → 6-chloro-N-(1-ethylpiperidin-4-yl)-1,2,3,4-tetrahydroacridin-9-amine

HRID 1506777Notes

Reaction equation

HRID 1506777 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:13](=[CH:14][CH:15]=1)[C:12](Cl)=[C:11]1[C:6]([CH2:7][CH2:8][CH2:9][CH2:10]1)=[N:5]2.[CH2:17]([N:19]1[CH2:24][CH2:23][CH:22]([NH2:25])[CH2:21][CH2:20]1)[CH3:18]>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:13](=[CH:14][CH:15]=1)[C:12]([NH:25][CH:22]1[CH2:23][CH2:24][N:19]([CH2:17][CH3:18])[CH2:20][CH2:21]1)=[C:11]1[C:6]([CH2:7][CH2:8][CH2:9][CH2:10]1)=[N:5]2

Participants

3

Reactant 2

HCID 2196646,9-Dichloro-1,2,3,4-tetrahydroacridineHCID 37349901-Ethylpiperidin-4-amine

Product 1

HCID 709837576-chloro-N-(1-ethylpiperidin-4-yl)-1,2,3,4-tetrahydroacridin-9-amine

Procedure

Following the general procedure of Example 1 and making non-critical variations but using 6,9-dichloro-1,2,3,4-tetrahydroacridine and 1-ethylpiperidin-4-amine, the title compound was obtained; MS (Found M+1=344).

Sources & evidence

ORD record
ord-de153b9d8e3440769f7611c840751163
Source dataset
uspto-grants-2015_12
Patent number
US09221760B2

Reaction notes

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