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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1506898Generated: October 31, 2026

4-Fluorobenzenesulfonyl chloride → Ethyl 2-(4-fluorobenzenesulphonylamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate

https://huagongshe.com/reaction/1506898

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzenesulfonyl chlorideHCID 9588—
ReactantEthyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylateHCID 78262—
ReactantEthyl 2-(benzenesulfonamido)-4,5,6,7-tetrahydrobenzothiophene-3-carboxylateHCID 391240—
ProductEthyl 2-(4-fluorobenzenesulphonylamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylateHCID 68278868—

Reaction Steps

Prepared by proceeding in a similar manner to Intermediate 1, starting from ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate and 4-fluorobenzene-sulphonyl chloride

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09221787B2
Source datasetuspto-grants-2015_12
ORD IDord-eb36245f711b4114b673f6ca415d2bd9
Source noteuspto-grants-2015_12