Benzenesulfonyl chloride → Ethyl 2-benzenesulphonylamino-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate

HRID 1506902Notes

Reaction equation

HRID 1506902 reaction equation
[C:1]1([S:7]([NH:10][C:11]2[S:15][C:14]3[CH2:16]C[CH2:18][CH2:19][C:13]=3[C:12]=2[C:20]([O:22][CH2:23][CH3:24])=[O:21])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.NC1SC2C[O:31]CCC=2C=1C(OCC)=O.C1(S(Cl)(=O)=O)C=CC=CC=1>>[C:1]1([S:7]([NH:10][C:11]2[S:15][C:14]3[CH2:16][O:31][CH2:18][CH2:19][C:13]=3[C:12]=2[C:20]([O:22][CH2:23][CH3:24])=[O:21])(=[O:9])=[O:8])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 3

HCID 7369Benzenesulfonyl chlorideHCID 391240Ethyl 2-(benzenesulfonamido)-4,5,6,7-tetrahydrobenzothiophene-3-carboxylateHCID 10987982Ethyl 2-amino-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxylate2×

Product 1

HCID 68278645Ethyl 2-benzenesulphonylamino-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate

Procedure

Prepared by proceeding in a similar manner to Intermediate 1, starting from ethyl 2-amino-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate (Intermediate 7) and benzenesulphonyl chloride

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-a4e9a6ba0b97463aacf02ed81898d702
Source dataset
uspto-grants-2015_12
Patent number
US09221787B2

Reaction notes

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