Benzenesulfonyl chloride → Ethyl 2-benzenesulphonylamino-5-phenylthiophene-3-carboxylate

HRID 1506903Notes

Reaction equation

HRID 1506903 reaction equation
[C:1]1([S:7]([NH:10][C:11]2[S:15][C:14]3[CH2:16][CH2:17][CH2:18][CH2:19][C:13]=3[C:12]=2[C:20]([O:22][CH2:23][CH3:24])=[O:21])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.N[C:26]1SC(C2C=CC=CC=2)=C[C:30]=1C(OCC)=O.C1(S(Cl)(=O)=O)C=CC=CC=1>>[C:1]1([S:7]([NH:10][C:11]2[S:15][C:14]([C:16]3[CH:17]=[CH:18][CH:19]=[CH:30][CH:26]=3)=[CH:13][C:12]=2[C:20]([O:22][CH2:23][CH3:24])=[O:21])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 3

HCID 7369Benzenesulfonyl chlorideHCID 391240Ethyl 2-(benzenesulfonamido)-4,5,6,7-tetrahydrobenzothiophene-3-carboxylateHCID 638860ethyl 2-amino-5-phenylthiophene-3-carboxylate

Product 1

HCID 68278877Ethyl 2-benzenesulphonylamino-5-phenylthiophene-3-carboxylate

Procedure

Prepared by proceeding in a similar manner to Intermediate 1, starting from ethyl 2-amino-5-phenylthiophene-3-carboxylate and benzenesulphonyl chloride

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-e1d781dfe50d42bb9df9ad74b420ce7b
Source dataset
uspto-grants-2015_12
Patent number
US09221787B2

Reaction notes

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