Pyridine → HCID 90017971, compound

Participants

Reaction Steps

To a stirred solution of (E)-5-phenylpent-3-en-1-ol (Preparation example 236, 3.8 g, 23.42 mmol) in CH2Cl2 (40 mL) was added pyridine (2.3 mL, 28.1 mmol) and pivaloyl chloride (3.5 mL, 28.1 mmol) at 0° C. under N2. The mixture was stirred for 14 h. The resulting mixture was diluted with CH2Cl2, washed with water, dried over MgSO4, filtered, and concentrated under reduced pressure. The crude compound was purified by a silica gel column to produce the title compound (5.5 g, 80˜95%)

Provenance & Evidence