HCID 11063699, compound → HCID 118151729, compound

HRID 1506972Notes

Reaction equation

HRID 1506972 reaction equation
[CH3:1][O:2][C:3](=[O:15])[C@@H:4]([OH:14])[C@H:5]([OH:13])[CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.O[C@H:17]([C@@H:22](O)[CH2:23][C:24]1C=CC=CC=1)[C:18](OC)=O>>[CH3:1][O:2][C:3]([C@@H:4]1[C@@H:5]([CH2:6][C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[O:13][C:22]([CH2:23][CH3:24])([CH2:17][CH3:18])[O:14]1)=[O:15]

Participants

3

Reactant 2

HCID 11063699HCID 11063699, compoundHCID 118151830HCID 118151830, compound

Product 1

HCID 118151729HCID 118151729, compoundYield 50%

Procedure

The substantially same method as described in Example 263 was conducted, except that (2S,3R)-methyl-2,3-dihydroxy-4-phenylbutanoate (Preparation example 269) was used instead of (2,3-dihydroxy-4-phenylbutanoate (Preparation example 260), to obtain the title compound (1.5 g, 50˜75%)

Sources & evidence

ORD record
ord-1cbca3d809e94f97aaccbbd30633eda8
Source dataset
uspto-grants-2015_12
Patent number
US09221783B2

Reaction notes

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