HCID 6105229, compound → HCID 90017589, compound

HRID 1506979Notes

Reaction equation

HRID 1506979 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8]/[CH:9]=[CH:10]/[CH2:11][C:12](O)=[O:13].C1(C/C=C/CC(O)=O)C=CC=CC=1>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8]/[CH:9]=[CH:10]/[CH2:11][CH2:12][OH:13]

Participants

3

Reactant 2

HCID 6105229HCID 6105229, compoundHCID 90018304HCID 90018304, compound

Product 1

HCID 90017589HCID 90017589, compoundYield 70%

Procedure

The substantially same method as described in Example 236 was conducted, except that (E)-5-(2-chlorophenyl)pent-3-enoic acid (Preparation example 302) was used instead of that (E)-5-phenylpent-3-enoic acid (Preparation example 235), to obtain the title compound (4.6 g, 70˜90%)

Sources & evidence

ORD record
ord-ce0987ea51ff45728ae7a9e58eff8d7f
Source dataset
uspto-grants-2015_12
Patent number
US09221783B2

Reaction notes

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