HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1507030Generated: October 31, 2026
Ethyl bromoacetate → HCID 86729446, compound
https://huagongshe.com/reaction/1507030
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethyl bromoacetate | HCID 7748 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5-Hydroxy-2H-1,4-benzoxazin-3(4H)-one | HCID 45789807 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86729446 | HCID 86729446 | — |
Reaction Steps
A solution of 5-hydroxy-2H-benzo[b][1,4]oxazin-3(4H)-one (100 mg, 0.604 mmol) and K2CO3 (167 mg, 1.21 mmol) in anhydrous DMF (5 mL) was stirred at 27° C. for 5 minutes, then ethyl 2-bromoacetate (121 mg, 0.727 mmol) was added. The reaction mixture was stirred at 27° C. for 16 h and concentrated. MS (ESI+) e/z: 238.0 [M+1]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09221794B2 |
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| Source dataset | uspto-grants-2015_12 |
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| ORD ID | ord-076261c1895d4fadb520b416152271bd |
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| Source note | uspto-grants-2015_12 |
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