Sodium borohydride → HCID 117739222, compound

Participants

Reaction Steps

By General Procedure U from ethyl 2-[(N-{3-[benzyl(methyl)amino]propyl}-2,2,2-trifluoroacetamido)methyl]pyridine-4-carboxylate using 5.0 equiv. of NaBH4. Purification by column chromatography gave the title product. 1H NMR (300 MHz, CDCl3) 8 ppm: 8.5 (dd, 1H), 7.80 (s, 1H), 7.6-7.3 (m, 1H), 4.6 (s, 2H), 4.3 (s, 2H), 3.6-3.2 (m, 4H), 2.8 (s, 3H), 2.2-2.0 (m, 2H), 1.7-1.3 (m, 3H).

Provenance & Evidence