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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1507288Generated: October 31, 2026

5-Bromo-2-(2-phenylacetamido)benzoate → 6-Bromo-3-(2-chlorophenyl)-4-hydroxyquinolin-2(1H)-one

https://huagongshe.com/reaction/1507288

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-(2-phenylacetamido)benzoateHCID 40548426—
Reactant6-Bromo-4-hydroxy-3-phenylquinolin-2(1H)-oneHCID 86716056—
ReactantMethyl 5-bromo-2-(2-(2-chlorophenyl)acetamido)benzoateHCID 86716059—
Product6-Bromo-3-(2-chlorophenyl)-4-hydroxyquinolin-2(1H)-oneHCID 86716058—

Reaction Steps

The title compound was prepared using methyl 5-bromo-2-(2-(2-chlorophenyl)acetamido)benzoate (Intermediate 2: step a) in place of 5-bromo-2-(2-phenylacetamido)benzoate using the procedure described for Intermediate 1: step b.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09221804B2
Source datasetuspto-grants-2015_12
ORD IDord-2a8690e2907941f4b67707c39cb06fcb
Source noteuspto-grants-2015_12