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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 150745Generated: October 30, 2026

1,2-Dichloroethane → 8-[[2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-phenyloxan-4-yl]methyl]-2-oxa-8-azaspiro[4.5]decan-4-ol

https://huagongshe.com/reaction/150745

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantHydrochloric AcidHCID 313—
ReactantSodium ionHCID 923—
ReactantTriethylamineHCID 8471—
ReactantTriacetoxyborohydrideHCID 2724942—
Reactant2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-phenyloxane-4-carbaldehydeHCID 18419662—
Reactant2-Oxa-8-azaspiro[4.5]decan-4-olHCID 21955364—
Product8-[[2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-phenyloxan-4-yl]methyl]-2-oxa-8-azaspiro[4.5]decan-4-olHCID 44216082—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-55215cbf18544a14b363b3848837b07f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)