Oxalyl chloride → 1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbonyl chloride

Participants

Reaction Steps

To 3-(Trifluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid (3.00 g, 15.5 mmol) suspended in dichloromethane was added oxalyl chloride (2.24 g, 17.8 mmol) and dimethylformamide (one drop). The reaction mixture was stirred at room temperature until bubbling stopped at which point the organic solution was evaporated in vacuo to obtain 3.25 g (99%) of the title compound.

Provenance & Evidence