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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1507479Generated: October 31, 2026

Cyclobutylamine → HCID 136984071, compound

https://huagongshe.com/reaction/1507479

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclobutylamineHCID 75645—
ReactantHCID 117677454HCID 117677454—
SolventAcetonitrileHCID 6342—
ProductHCID 136984071HCID 136984071—

Reaction Conditions

Temperature80 °C

Reaction Steps

Compound 8 (100 mg, 0.197 mmol) was dissolved in MeCN (2 mL) and cyclobutylamine (168 μL, 1.97 mmol) was added. The reaction was heated to 80° C. for 1 h. The solvent was evaporated and the residue was purified by column chromatography on silica gel, eluting with EtOAc/hexane to give the title compound as a yellow solid. MS 498 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09221809B2
Source datasetuspto-grants-2015_12
ORD IDord-162f79eb845043cfa5ce17764691c4e8
Source noteuspto-grants-2015_12