Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Cyclobutylamine | HCID 75645 | — |
| Reactant | HCID 117677454 | HCID 117677454 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 136984071 | HCID 136984071 | — |
Reaction Steps
Compound 8 (100 mg, 0.197 mmol) was dissolved in MeCN (2 mL) and cyclobutylamine (168 μL, 1.97 mmol) was added. The reaction was heated to 80° C. for 1 h. The solvent was evaporated and the residue was purified by column chromatography on silica gel, eluting with EtOAc/hexane to give the title compound as a yellow solid. MS 498 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09221809B2 |
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| Source dataset | uspto-grants-2015_12 |
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| ORD ID | ord-162f79eb845043cfa5ce17764691c4e8 |
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| Source note | uspto-grants-2015_12 |
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