2-(Trifluoromethyl)benzoyl chloride → [4-(6-Phenylpyridazin-3-YL)piperazin-1-YL]-(2-trifluoromethylphenyl)methanone

HRID 150754Notes

Reaction equation

HRID 150754 reaction equation
[F:19][C:20]([c:21]1[c:22]([C:23](=[O:24])[Cl:25])[cH:26][cH:27][cH:28][cH:29]1)([F:30])[F:31].[c:1]1(-[c:7]2[n:8][n:9][c:10]([N:13]3[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]3)[cH:11][cH:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[n:8][n:9][c:10]([N:13]3[CH2:14][CH2:15][N:16]([C:23]([c:22]4[c:21]([C:20]([F:19])([F:30])[F:31])[cH:29][cH:28][cH:27][cH:26]4)=[O:24])[CH2:17][CH2:18]3)[cH:11][cH:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

3

Reactant 2

HCID 675612-(Trifluoromethyl)benzoyl chlorideHCID 99918883-Phenyl-6-(piperazin-1-yl)pyridazine

Product 1

HCID 11675961[4-(6-Phenylpyridazin-3-YL)piperazin-1-YL]-(2-trifluoromethylphenyl)methanone

Sources & evidence

ORD record
ord-abd2b254513f4eefab93dad029bdab34
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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