2-Chloroisonicotinic acid → HCID 73425725, compound

HRID 1507569Notes

Reaction equation

HRID 1507569 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][N:10]=1)[C:5]([OH:7])=O.[NH2:11][C:12]1[C:20]([CH3:21])=[C:19]2[C:15]([C:16]([CH3:25])([CH3:24])[C:17](=[O:23])[N:18]2[CH3:22])=[CH:14][CH:13]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][N:10]=1)[C:5]([NH:11][C:12]1[C:20]([CH3:21])=[C:19]2[C:15]([C:16]([CH3:25])([CH3:24])[C:17](=[O:23])[N:18]2[CH3:22])=[CH:14][CH:13]=1)=[O:7]

Participants

3

Reactant 2

HCID 2369852-Chloroisonicotinic acidHCID 90046352HCID 90046352, compound

Product 1

HCID 73425725HCID 73425725, compound

Procedure

Prepared in analogy to example 26 from 2-chloroisonicotinic acid and 6-amino-1,3,3,7-tetramethyl-1,3-dihydro-indol-2-one. The title compound was obtained as light yellow crystals.

Sources & evidence

ORD record
ord-fce315aacb4c45e499cf4fd5125310c3
Source dataset
uspto-grants-2015_12
Patent number
US09221816B2

Reaction notes

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