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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 150758Generated: October 26, 2026

1,4-Dioxane → N-(4-(Trifluoromethyl)phenyl)-5,6,7,8-tetrahydro-7-(3-(methylsulfonyl)pyridin-2-yl)-2-(methylthio)pyrido[3,4-d]pyrimidin-4-amine

https://huagongshe.com/reaction/150758

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DioxaneHCID 31275—
ReactantDiisopropylethylamineHCID 81531—
Reactant2-Chloro-3-(methanesulfonyl)pyridineHCID 12513746—
ReactantN-(4-(Trifluoromethyl)phenyl)-5,6,7,8-tetrahydro-2-(methylthio)pyrido[3,4-d]pyrimidin-4-amineHCID 59021576—
ProductN-(4-(Trifluoromethyl)phenyl)-5,6,7,8-tetrahydro-7-(3-(methylsulfonyl)pyridin-2-yl)-2-(methylthio)pyrido[3,4-d]pyrimidin-4-amineHCID 59021572—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-effc8a7686e845dcab367a4642240a85
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)