3-Fluoropyridine-4-carboxylic acid → HCID 73426058, compound

HRID 1507581Notes

Reaction equation

HRID 1507581 reaction equation
[F:1][C:2]1[CH:10]=[N:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[NH2:11][C:12]1[CH:20]=[C:19]2[C:15]([C:16]([CH3:28])([CH3:27])[C:17](=[O:26])[N:18]2[CH:21]2[CH2:25][CH2:24][CH2:23][CH2:22]2)=[CH:14][CH:13]=1>>[CH:21]1([N:18]2[C:19]3[C:15](=[CH:14][CH:13]=[C:12]([NH:11][C:4](=[O:6])[C:3]4[CH:7]=[CH:8][N:9]=[CH:10][C:2]=4[F:1])[CH:20]=3)[C:16]([CH3:27])([CH3:28])[C:17]2=[O:26])[CH2:22][CH2:23][CH2:24][CH2:25]1

Participants

3

Reactant 2

HCID 3453613-Fluoropyridine-4-carboxylic acidHCID 90047533HCID 90047533, compound

Product 1

HCID 73426058HCID 73426058, compound

Procedure

Prepared in analogy to example 26 from 3-fluoroisonicotinic acid and 6-amino-1-cyclopentyl-3,3-dimethyl-1,3-dihydro-indol-2-one. The title compound was obtained as yellow foam.

Sources & evidence

ORD record
ord-5442367c21c54d99a1fa1318a852d6bc
Source dataset
uspto-grants-2015_12
Patent number
US09221816B2

Reaction notes

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