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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1507592Generated: October 31, 2026

3-Fluoropyridine-4-carboxylic acid → N-(1-(3-Cyclopropoxypropyl)-3,3-dimethyl-2-oxoindolin-6-yl)-3-fluoroisonicotinamide

https://huagongshe.com/reaction/1507592

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoropyridine-4-carboxylic acidHCID 345361—
Reactant6-Amino-1-(3-cyclopropoxypropyl)-3,3-dimethylindolin-2-oneHCID 90046308—
ProductN-(1-(3-Cyclopropoxypropyl)-3,3-dimethyl-2-oxoindolin-6-yl)-3-fluoroisonicotinamideHCID 73426356—

Reaction Steps

Prepared in analogy to example 26 from 6-amino-1-(3-cyclopropoxypropyl)-3,3-dimethylindolin-2-one and 3-fluoroisonicotinic acid. The title compound was obtained as yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09221816B2
Source datasetuspto-grants-2015_12
ORD IDord-314e81ee51c64b419bfe97a4b0a2a8d9
Source noteuspto-grants-2015_12