2-Methylpyridine-4-carboxylic acid → HCID 73426647, compound

HRID 1507604Notes

Reaction equation

HRID 1507604 reaction equation
Cl.[NH2:2][C:3]1[N:8]=[C:7]2[N:9]([CH3:15])[C:10](=[O:14])[C:11]([CH3:13])([CH3:12])[C:6]2=[CH:5][CH:4]=1.[CH3:16][C:17]1[CH:18]=[C:19]([CH:23]=[CH:24][N:25]=1)[C:20](O)=[O:21]>>[CH3:16][C:17]1[CH:18]=[C:19]([CH:23]=[CH:24][N:25]=1)[C:20]([NH:2][C:3]1[N:8]=[C:7]2[N:9]([CH3:15])[C:10](=[O:14])[C:11]([CH3:12])([CH3:13])[C:6]2=[CH:5][CH:4]=1)=[O:21]

Participants

3

Reactant 2

HCID 27628212-Methylpyridine-4-carboxylic acidHCID 90047521HCID 90047521, compound

Product 1

HCID 73426647HCID 73426647, compound

Procedure

Prepared in analogy to example 26 using 6-amino-1,3,3-trimethyl-1H-pyrrolo[2,3-b]pyridin-2(3H)-one hydrochloride (example 76c) and 2-methylisonicotinic acid. The title compound was obtained as light brown viscous oil.

Sources & evidence

ORD record
ord-893e2de319794b0abd8e0170a03c967c
Source dataset
uspto-grants-2015_12
Patent number
US09221816B2

Reaction notes

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