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2-Methylpyrimidine-5-carboxylic acid → N-(1-Cyclopropyl-3,3-dimethyl-2-oxo-2,3-dihydro-1H-pyrrolo[3,2-c]pyridin-6-yl)-2-methylpyrimidine-5-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Methylpyrimidine-5-carboxylic acid | HCID 13670875 | — |
| 反応物 | 6-Amino-1-cyclopropyl-3,3-dimethyl-1H-pyrrolo[3,2-c]pyridin-2(3H)-one | HCID 90047516 | — |
| 生成物 | N-(1-Cyclopropyl-3,3-dimethyl-2-oxo-2,3-dihydro-1H-pyrrolo[3,2-c]pyridin-6-yl)-2-methylpyrimidine-5-carboxamide | HCID 73426546 | — |
反応手順
Prepared in analogy to example 26 from 2-methylpyrimidine-5-carboxylic acid and 6-amino-1-cyclopropyl-3,3-dimethyl-1H-pyrrolo[3,2-c]pyridin-2(3H)-one (example 79c). The title compound was obtained as light yellow crystals.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09221816B2 |
| 出典データセット | uspto-grants-2015_12 |
| ORD ID | ord-a7995854d3fc4207a75d6282bdfc0178 |
| 出典メモ | uspto-grants-2015_12 |