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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1507614Generated: October 25, 2026

3-Methyl-1,2-oxazole-4-carboxylic acid → N-(1-Cyclopropyl-3,3-dimethyl-2-oxo-2,3-dihydro-1H-pyrrolo[3,2-c]pyridin-6-yl)-3-methylisoxazole-4-carboxamide

https://huagongshe.com/reaction/1507614

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-1,2-oxazole-4-carboxylic acidHCID 4589692—
Reactant6-Amino-1-cyclopropyl-3,3-dimethyl-1H-pyrrolo[3,2-c]pyridin-2(3H)-oneHCID 90047516—
ProductN-(1-Cyclopropyl-3,3-dimethyl-2-oxo-2,3-dihydro-1H-pyrrolo[3,2-c]pyridin-6-yl)-3-methylisoxazole-4-carboxamideHCID 73426551—

Reaction Steps

Prepared in analogy to example 26 from 3-methylisoxazole-4-carboxylic acid and 6-amino-1-cyclopropyl-3,3-dimethyl-1H-pyrrolo[3,2-c]pyridin-2(3H)-one (example 79c). The title compound was obtained as light brown viscous oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09221816B2
Source datasetuspto-grants-2015_12
ORD IDord-3e2ab4a64b044f7e9c81fc116fc7065e
Source noteuspto-grants-2015_12