HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide → Sildenafil
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide | HCID 3338044 | — |
| Reactant | HCID 54158580 | HCID 54158580 | — |
| Product | Sildenafil | HCID 135398744 | — |
Reaction Steps
An reaction between 1-methyl-3-propyl-4-aminopyrazole-5-carboxamide and 2-ethoxy-5-(4-methylpiperazine-1-sulfonyl)-benzoyl chloride is performed, and then Sildenafil is obtained by ring closure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09221825B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-0efa5b7169a44c14b785c9ab6f74c71b |
| Source note | uspto-grants-2015_12 |