Trifluoroacetic acid → HCID 89614828, compound

Participants

Reaction Steps

TFA (1.5 mL, 19.3 mmol) was added dropwise to a stirred solution of tert-butyl 25,25-dimethyl-2,5,8,11,14,17,20,23-octaoxahexacosan-26-oate (58) (0.48 g, 0.97 mmol) in DCM (5 mL), and the reaction was stirred at RT for 4 h. The volatiles were removed in vacuo to afford 25,25-dimethyl-2,5,8,11,14,17,20,23-octaoxahexacosan-26-oic acid (59) (0.49 g, 95%) as a colourless oil: 1H NMR (400 MHz, CDCl3) δ: 3.68-3.60 (m, 26H), 3.55-3.52 (m, 2H), 3.47 (s, 2H), 3.36 (s, 3H), 1.18 (s, 6H).

Provenance & Evidence