(4-Chlorophenoxy)acetic acid → 1-(4-(5-Amino-2-(4-methylphenethyl)thiazolo[5,4-d]pyrimidin-7-yl)piperazin-1-yl)-2-(4-chlorophenoxy)ethanone

Participants

Role	Name	HCID	Charge
Reactant	(4-Chlorophenoxy)acetic acid	HCID 26229	—
Reactant	2-(4-Methylphenethyl)-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidin-5-amine	HCID 66759053	—
Product	1-(4-(5-Amino-2-(4-methylphenethyl)thiazolo[5,4-d]pyrimidin-7-yl)piperazin-1-yl)-2-(4-chlorophenoxy)ethanone	HCID 66758552	51%

Reaction Steps

This compound was prepared from 2-(4-methylphenethyl)-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidin-5-amine using 4-chlorophenoxyacetic acid in a yield of 51%, according to the procedure for the synthesis of example 50.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09221822B2
Source dataset	uspto-grants-2015_12
ORD ID	ord-7836c0d9c47640608a9267d64251c64b
Source note	uspto-grants-2015_12