(4-Chlorophenoxy)acetic acid → HCID 50942247, compound

HRID 1507840Notes

Reaction equation

HRID 1507840 reaction equation
[N:1]1([C:7]2[C:8]3[N:16]=[C:15]([C:17]4[CH:22]=[CH:21][N:20]=[CH:19][CH:18]=4)[S:14][C:9]=3[N:10]=[C:11]([NH2:13])[N:12]=2)[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[Cl:23][C:24]1[CH:34]=[CH:33][C:27]([O:28][CH2:29][C:30](O)=[O:31])=[CH:26][CH:25]=1>>[NH2:13][C:11]1[N:12]=[C:7]([N:1]2[CH2:6][CH2:5][N:4]([C:30](=[O:31])[CH2:29][O:28][C:27]3[CH:33]=[CH:34][C:24]([Cl:23])=[CH:25][CH:26]=3)[CH2:3][CH2:2]2)[C:8]2[N:16]=[C:15]([C:17]3[CH:22]=[CH:21][N:20]=[CH:19][CH:18]=3)[S:14][C:9]=2[N:10]=1

Participants

3

Reactant 2

HCID 26229(4-Chlorophenoxy)acetic acidHCID 50942058HCID 50942058, compound

Product 1

HCID 50942247HCID 50942247, compoundYield 43%

Procedure

This compound was prepared from 7-(piperazin-1-yl)-2-(pyridin-4-yl)thiazolo[5,4-d]pyrimidin-5-amine using 4-chlorophenoxyacetic acid in a yield of 43%, according to the procedure for the synthesis of example 50.

Workup

  1. customaccording to the procedure for the synthesis of example 50

Sources & evidence

ORD record
ord-8277657aee30429caf448c30567af6ea
Source dataset
uspto-grants-2015_12
Patent number
US09221822B2

Reaction notes

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