HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzoic Acid → 2-(4-Fluorophenyl)-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzoic Acid | HCID 9973 | — |
| Reactant | Tert-butyl 4-(5-amino-6-mercaptopyrimidin-4-yl)piperazine-1-carboxylate | HCID 178452266 | — |
| Product | 2-(4-Fluorophenyl)-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidine | HCID 66758175 | 74% |
Reaction Steps
This compound was synthesized from tert-butyl 4-(5-amino-6-mercaptopyrimidin-4-yl)piperazine-1-carboxylate using 4-fluorobenzoic acid, yielding the title compound in 74% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09221822B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-0be4119f28d94b30a358ef0cee7b5939 |
| Source note | uspto-grants-2015_12 |