4-Methoxyphenoxyacetic acid → HCID 66758829, compound

Participants

Reaction Steps

This compound was prepared from 2-(4-bromophenethyl)-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidin-5-amine using 4-methoxyphenoxyacetic acid in a yield of 40%, according to the procedure for the synthesis of example 50. 1H NMR (300 MHz, CDCl3, 25° C.): δ=7.40 (d, 2H, PhH), 7.07 (d, 2H, PhH), 6.82-6.93 (m, 4H, PhH), 4.71 (s, 2H, NH2), 4.70 (s, 2H, OCH2), 4.23 (br s, 2H, NCH2), 4.19 (br s, 2H, NCH2), 3.77 (s, 3H, CH3), 3.67-3.75 (m, 4H, N(CH2)2), 3.23 (t, 2H, CH2), 3.05 (t, 2H, CH2) ppm

Provenance & Evidence