Methyl iodide → HCID 56940731, compound

HRID 1507885Notes

Reaction equation

[NH2:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[C:7]([S:11][CH3:12])[NH:8]2)=[C:4]([N:13]2[CH2:18][CH2:17][N:16]([C:19](=[O:29])[CH2:20][O:21][C:22]3[CH:27]=[CH:26][C:25]([Cl:28])=[CH:24][CH:23]=3)[CH2:15][CH2:14]2)[N:3]=1.[CH3:30]I>>[NH2:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[C:7]([S:11][CH3:12])[N:8]2[CH3:30])=[C:4]([N:13]2[CH2:18][CH2:17][N:16]([C:19](=[O:29])[CH2:20][O:21][C:22]3[CH:27]=[CH:26][C:25]([Cl:28])=[CH:24][CH:23]=3)[CH2:15][CH2:14]2)[N:3]=1

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 178503358HCID 178503358, compound

Product 1

HCID 56940731HCID 56940731, compoundYield 97%

Procedure

This compound was synthesized from 2-amino-6-[4-(4-chlorophenoxyacetyl)piperazin-1-yl]-8-methylthio-9H-purine using methyl iodide, yielding the title compound in 97% yield.

Sources & evidence

ORD record: ord-9a267416991d436f946e9cc0c71f797c
Source dataset: uspto-grants-2015_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09221822B2

Reaction notes

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